Background: Survival rates for children who require intensive care for the
treatment of life-threatening illness or injury have dramatically improved worldwide. In
pediatric critical care, decreased mortality has been accompanied by increased morbidity.
This has resulted in a shift in the contemporary focus of the international critical care
community from mortality reduction alone to the optimization of survivor outcomes. Aim:
to assess nurses' knowledge and their practices regarding post intensive care syndrome of
critically ill pediatric patients. Method: adescriptivedesign has been used to conduct this
study in the Pediatric Medical Intensive Care Unit affiliated with the Mansoura University
Children's Hospital, was conducted withall available nurses in pediatric intensive care
setting. Data was collected by using a questionnaire sheet for socio-demographic
characteristics and knowledge and observational checklists for practices were used to
collect data. Results: the vast majority of the studied nurses had insufficient knowledge
about post intensive care syndrome and ABCDEF bundleand almost of them had
unsatisfactory practices about ABCDEF bundle. Recommendation: it is recommended to
implement educational intervention for nurses about post intensive care syndrome to
improve their knowledge and practices about PICS and ABCDEF bundle.