Due to shortage of local research in Saudi Arabia dealing with land use planning in general and service-related commercial land use in specific, there is a lack of sound understanding among professionals dealing with land use planning, which in turn causes a large disparity in urban structure in the current Saudi cities. The main goal of the study is to determine the factors affecting service-related commercial land use pattern in Alkhobar City, in the Eastern Province of the Kingdom of Saudi Arabia. The study accomplished this aim by conducting a literature review and a field questionnaire survey applied on a sample of planning experts to verify stated hypothesis defining the factors affecting service-related commercial land use pattern. Principle Component Analysis and Regression Analysis were used to define these factors and the level of impact for each foctor. The study found that service-related commercial land use pattern is determined by factors related to the site spatial planning and regulations and strategic issues. These factors include road width, availability of landscape elements, accessibility, mobility, land use regulations, land use mechanism and availability of commercial lands for population.