This study was carried out to estimate genetic parameters and environmental factors which affect milk production and milking-ability traits in a herd of Holstein Friesian raised under Egyptian conditions via animal model. The data were collected from six herds from a commercial farm called Dina for agriculture investment, located in Cairo-Alexandria desert road (80 Km) from Cairo, Menoufia, Egypt. Data included 3881 cows as progenies of 3321 dams and 261 sires in 6 herds that represented the period from 2007 to 2014.  The least square mean (LSM ±SD) and coefficient of variability (CV%) of milk traits as total milk yield (TMY), 305-day milk yield (305-dMY) are 10486 ±2366 kg (% 22.6), and 9399 ±1767 kg (% 18.8), respectively. Also, the LSM of milking-ability traits as average flow rate (AFR), peak flow rate (PF) and milking duration (MD) are 2.21±0.78 kg/min (% 35.3), 3.93±1.0 kg/min (% 25.5), and 4.09 ±1.29 min (% 31.5), respectively. Finally, the mean of age at first calving (AFC) is 24.8±2.3 month (% 9.2). Sire, dam, and non-genetic factors as herd, parity of cow, year and season of calving had significant effects on studied traits. Heritability estimates for TMY, 305-dMY, AFC, AFR, PF and MD were 0.11, 0.27, 0.25, 0.20, 0.07 and 0.09, respectively. Moderate heritability estimates and positive genetic correlation for most of studied traits suggested that genetic improvement of these traits would be achieved via multi-trait selection.