This research aimed to identify the level of knowledge and implementation of the practices of waste reduction in the study area and determine the problems. The study was limited to Menoufia Governorate Egypt. as one of the largest governorates in wheat cultivation, in the center of Ashmoun district, in the villages of "Smadon" and "Talia". The total sample size was 361 holders. The questionnaire was used by personal interview and collected during the months of May and June 2021. "Pearson correlation coefficient", and upward stepwise multiple linear regression analysis were used, and the "P" test was used to judge the significance of the analytical models, the most important results were: the level of wheat growers' knowledge of waste reduction recommendations was high, the level of implementation of the recommendations to reduce losses was moderate, and the most important recommendations were: choosing the appropriate variety for the nature of the region, automatic harvesting of the wheat crop, the most important technical reasons for the loss are: irrigating the crop at winday times ( which cause lodging, the most important marketing reasons for the loss: the infestation of insect pests such as weevils, and the exposure of the crop to fire, especially in the jar, and the most important social and cultural reasons: harvesting wheat in the milky phase for profit-generating activities and using seeds from stored grains from last year.