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78457

PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMI

Article

Last updated: 25 Dec 2024

Subjects

-

Tags

General Applied Sciences

Abstract

A series of new thioxopyrimidine, 4H-pyrans, pyranopyridine and pyranopyrimidine derivatives with expected biological activity have been prepared through the reaction of 6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(5H)-one 4 and 7-Amino-5-(4-chlorophenyl)-4-phenyl-2-thioxo-2,5-dihydro-1H-pyrano[2,3-d]pyrimidine-6-carbonitrile 11b with some electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, 1H-NMR and mass spectral studies.

DOI

10.21608/sinjas.2014.78457

Keywords

Thioxopyrimidine, 4H-pyrans, pyranopyridine and pyranopyrimidine

Authors

First Name

Mohamed

Last Name

Elian

MiddleName

A.

Affiliation

Dept. Chem., Fac. Educ., Suez Canal Univ., Arish, Egypt.

Email

-

City

North Sinai

Orcid

-

First Name

Ibrahim

Last Name

AbdelHafiz

MiddleName

S.

Affiliation

Dept. Chem., Fac. Educ., Suez Canal Univ., Arish, Egypt.

Email

-

City

Cairo

Orcid

-

First Name

Mohamed

Last Name

AbdElReheim

MiddleName

A.M.

Affiliation

Dept. Chem., Fac. Educ., Suez Canal Univ., Arish, Egypt.

Email

-

City

North Sinai

Orcid

-

Volume

3

Article Issue

2

Related Issue

11711

Issue Date

2014-08-01

Receive Date

2020-03-22

Publish Date

2014-08-01

Page Start

51

Page End

62

Print ISSN

2314-6079

Online ISSN

2682-3527

Link

https://sinjas.journals.ekb.eg/article_78457.html

Detail API

https://sinjas.journals.ekb.eg/service?article_code=78457

Order

2

Type Code

1,210

Publication Type

Journal

Publication Title

Sinai Journal of Applied Sciences

Publication Link

https://sinjas.journals.ekb.eg/

MainTitle

PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE

Details

Type

Article

Created At

22 Jan 2023