This experiment was carried out during 2009 to 2012 in order to study the toxicological effect of petroleum ether, acetone and methanol extracts from some Sinai's Flora Ader Artemisia monosperma (whole plant), Neem Azadirachta indica (fruits), Lantana Lantana camara (whole plant) and Tobacco Nicotiana glauca (leaves + flowers) against adults of rice weevil Sitophilus oryzae and broad bean beetle Bruchus rufimanus at the Laboratory. Results indicated that all methanol extracts (polar solvent) achieved a high toxicity action against adults of rice weevil S. oryzae compared with petroleum ether (non-polar solvent) and acetone (Semi-polar solvent). Also, it can concluded that Tobacco tree (Nicotiana glauca) is one of the most potent plant at different solvents (petroleum ether, acetone and methanol) against adults of rice weevil S. oryzae.