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74578

SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES

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Last updated: 04 Jan 2025

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Abstract

Fourteen new oxamides were synthesized by amidation of ethyl N-(2-methyl-4-oxoquinazolin-3-yl) oxamate with the appropriate amines. Preliminary anticonvulsant activity of five oxamides was evaluated, Correlation of activity with structure of the test compounds is also discussed.

DOI

10.21608/bfsa.1986.74578

Authors

First Name

A.

Last Name

Abdel-Alim

MiddleName

M.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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First Name

S.

Last Name

Hussein

MiddleName

A.

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

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Orcid

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First Name

H.

Last Name

El-Bitar

MiddleName

I.

Affiliation

Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt

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City

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Orcid

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First Name

R.

Last Name

Abdel-Aal

MiddleName

A.

Affiliation

Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt

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Volume

9

Article Issue

2

Related Issue

11260

Issue Date

1986-12-01

Receive Date

1986-06-24

Publish Date

1986-12-31

Page Start

78

Page End

91

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 9_Issue 2_Pages 78-91.pdf

PDF . 430.4kB

Link

https://bpsa.journals.ekb.eg/article_74578.html

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https://bpsa.journals.ekb.eg/service?article_code=74578

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Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME N-SUBSTITUTED-N'-(2-METHYL-4-OXOQUINAZOLIN-3-YL) OXAMIDES

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Article

Created At

22 Jan 2023