Background: Staff nurses are in need for praise and recognition because of its impact on their performance and their job satisfaction. Aim:evaluate effect of implementing meaningful recognition program on head nurses' knowledge and practice and nurses' satisfaction. Method: Quasi- experimental design was used to conduct the study at Tanta International Teaching Hospital. The subjects of the study consisted of all (35) head nurses and 250 staff nurses were working in the above mentioned setting. Three tools were utilized: Tool I: Head Nurses' Meaningful Recognition Process Observation Checklist. Tool II Head Nurses' Meaningful Recognition Process Knowledge Questionnaires. Tool III: Staff Nurses' Satisfaction of Head Nurses 'Practice of Meaningful Recognition Process questionnaire. Results: 91.4% of head nurses had unsatisfactory level regarding overall practice of meaningful recognition process at pre educational program, decreased to 14.3% post educational program and reached 42.9% at 3 months post educational program. 77.1% of head nurses had poor level of meaningful recognition knowledge at pre educational program, improved to be 88.6% good level at post and 82.9% post 3 month of the meaningful recognition educational program. Statistical significant positive correlation was found between head nurses' overall knowledge of meaningful recognition process, its subscales and their overall practice of meaningful recognition process and its subscales with their staff nurses' overall satisfaction of head nurses' practice of meaningful recognition process and its overall subscale at p≤ 0.05.Conclusion:Head nurses at Tanta International Teaching Hospital knowledge and practice positively improved post educational program of meaningful recognition , thus staff nurses had high level of satisfaction post program than pre program . So, nurse managers should pay more attention to the vital role of meaningful recognition as a valuable strategy for upgrading nurses' job satisfaction, and develop policies and practices that foster meaningful recognition among head nurses.