This study aimed to evaluate evidence based nurses' practice for children undergoing abdominal stoma outcome. Materials and Method: A quasi-experimental design was utilized in this study, that was conducted in Pediatric Surgical Department of Tanta University Hospital. All available nurses (40 nurses) working in previously mentioned setting and a purposive sample of 40 children divided into two equal groups and admitted to pediatric surgical unit undergoing abdominal stoma operation were taken from the above mentioned setting. Structured questionnaire schedule to assess socio demographic data of nurses and children , Nurses' knowledge regarding to stoma care 2) Nurses performance checklist regarding stoma care , peristomal skin observation checklist to observe the quality of nursing care provided for children undergoing stoma operation and detect the extent and severity of stoma and peristomal skin complications. Results : most of the nurses had poor levels of knowledge and performance related to stoma operation before application of evidence based practice and their knowledge and performance improved immediately and post three months of evidence based practice Moreover ,conditions of stomas and peristomal skin improved after nurses practiced evidence based practice. Conclusion : On the light of the current study results, it can be concluded that educational and training program was effective regarding improvement of nurses' knowledge and performance. Recommendations: continuing periodically in-service training programs should be introduced to the nurses on regular basis by different methods and materials of teaching .