Field trials were carried out at Sids Agricultural Research Station in 2015 and 2016 growing seasons. In 2015, 18 cotton genotypes were self- pollinated. In 2016, the genotypes were grown in a randomized complete block design with three replications. A random sample of four guarded plants of each genotype was chosen from each plot to determine some technological traits. The tested technological traits were fibre length at 2.5% (mm), fibre length uniformity ratio (%), and fibre strength (g/tex). The genotypes were screened under greenhouse conditions in 2017 against a mixture of 50 isolates (race3) of the wilt fungus. Healthy survival rate (HSR) was used as a criterion to evaluate the reaction of tested genotypes to Fusarium wilt. Nine (50%) of the tested genotypes were very highly resistant. Within this group, HSR ranged from 91.67 to 100% such as genotypes 1,3,4 and 5 with no significant differences. The significant correlations between some of the technological traits and some of the wilt symptoms were sensitive to changing environmental conditions, that is, the significant correlation in one year was nonsignificant in the other year. Grouping the genotypes by cluster analysis based on the profiles of their fiber traits was not related to their reaction class (resistance level). The results of the present study demonstrated that resistance to Fusarium wilt symptoms of fusarium wilt may positively or negatively affect the technological traits depending on the trait under consideration and the prevailing environmental conditions during cotton growing season.