Background: Varicose veins are chronic venous disorder described as enlarged, twisted, superficial veins caused by incompetent venous valves. It affects the lower limbs and quality of life of patients negatively. Aim: to determine the prevalence of varicose veins among secondary schools' teachers at Assiut Governorate. Methods: Descriptive - cross sectional research design had been used. The study was conducted at 4 districts which were randomly selected by using simple random sample to select the schools (3 schools in each district). The total number of the study sample was 500 teachers. Tools: - Three tools were used; the first tool was a structured self-administered questionnaire for demographic data, medical history, and risk factors. The second tool Venous Insufficiency Epidemiological and Economic Study – symptoms (VEINES- Sym) questionnaire. The third tool was clinical examination and Arterial color coded duplex scanning. Results: Prevalence of varicose veins among secondary schools' teachers in Assiut Governorate was 25.6%, 62.5% of them are females while 37.5% are males. Conclusion Varicose veins were widely spread among secondary schools' teachers in Assiut Governorate. Recommendations Health education program is very useful to prevent varicose veins and its complications.