The aim of this study to assessing the effect of structural and Psychological empowerment on newly graduated nurses' organizational commitment. Setting the study was conducted at Assiut University Hospitals, Health Insurance Hospital and two hospitals affiliated to Ministry of Health namely: Assiut General Hospital (El-Shamla Hospital) and El-Eman General Hospital in Assiut city Design descriptive correlational design was used. Subject It included all staff nurses who had at most two years' experience (136). Tools data collection tools were socio demographic data sheet, structural empowerment (conditions of work effectiveness questionnaire), psychological empowerment questionnaire, and organizational commitment scale. Results more than half of new graduated nurses reported high structural empowerment in ministry of health hospital compared with other two hospitals. Majority of nurses in different hospitals are psychologically empowered. Conclusion There was a weak negative relationship between structural empowerment and organizational commitment. Also, there was a moderate negative relationship between psychological empowerment and organizational commitment. Recommendation Carry out job orientation program for newly graduated nurses at the beginning of employment with the profession of employee policy handbook.