Transurethral cystolithotripsy is the most common way to manage cystolithiasis. Aim of this study: Was to evaluate the effect of implementing nursing preparations on improving patients' pain and satisfaction. Patients and methods Randomized Control Study design saw utilized to conduct this study. This study was carried out in the Urology and Nephrology Assiut University Hospital. A random sample of 60 adult patients of both sexes, the mean age of study group (51.20±11.73) and the mean age of control group (49.36±12.49). Patients were divided into two equal groups (study and control) 30 patients for each. Tools: Tool (I): Patient assessment sheet, tool (II): Pain numeric rating scale and tool (III): patient satisfaction with nursing care quality questionnaire. Results: Statistically significant differences were found between study and control groups post implementing nursing preparations as regard pain level and patients satisfaction. Conclusion: Significant pain improvement and high level of satisfaction were observed throughout implementation of the nursing preparations among the study group.