Quality Tools should positively effect on assessment of student's knowledge and practice regarding COVID 19. Aim of study was to study the effect of using quality tools on assessment of Health Technical Institution student's knowledge and practice regarding COVID 19. A descriptive study was utilized. Study was conducted at Port-Said City, in Health Technical Institute. The subjects involved all student at first and second academic year 2020 – 2021 and students' age ranged from 18 to 20 years old so, the sample size was 120 students. Data were collected through two quality tools; a questionnaire sheet, observational check lists. Results of study revealed that, majority (90%) of students had correct knowledge about symptoms, mode of transmission and preemptive action of COVID-19, and (33%) only knew about treatment approaches, but (49.20%) knew about vaccine against COVID19. Almost half (53.30%) of them preferred social media as primary sources of information followed. Most students showed a willingness to follow social distancing. Study concluded that using quality tools had positive effect on assessment of student's knowledge and practice regarding COVID 19 among health technical institute students. Authors recommended integrating a preemptive actions guideline regarding COVID 19 in the educational strategies at all educational stages.