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223251

Correlation between Diabetic Cystoid Macular Edema and Best Corrected Visual Acuity after Intravitreal Injection of Ranibizumab

Article

Last updated: 22 Jan 2023

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Tags

Clinical Research (Surgical)

Abstract

Background: Diabetic macular edema is a general term defined as retinal thickening within two-disc diameters of the foveal center; it can be either focal or diffuse in distribution.Intravitreal injection of anti-vascular endothelial growth factor (Ranibizumab) was approved for the treatment of diabetic macular edema. Objective:Assessment of correlation between diabetic cystoid macular edema and best-corrected visual acuity (BCVA) after intravitreal injection of Ranibizumab. Patients and Methods: Quasi-experimental interventional study was undertaken at Suez Canal University Hospital, Ophthalmology Department on patients who were diagnosed as having diabetic cystoid macular edema (CME) by optical coherence topography. A total of 60 participants were evaluated by taking a complete ophthalmologic history, examination, and investigations using a pre-designed checklist, and intravitreal injection of anti-VEGF was done. Results: Our study showed that the study group consisted of 71.4% females and 28.3% males. In our study group, we found that the Mean ± SD. In CME 3.50 ± 0.50 pre-VEGF injection, 2.0 ± 0.82 post VEGF injection with improvement1.50±0.50 (44.44%). The mean of BCVA in decimal among participants was 0.15 ± 0.06 pre-VEGF injection while 0.25 ± 0.07 post-VEGF injection with an improvement of 0.10 ± 0.03 (25.0%). There was strong relation and statistically significant. Conclusion: Intravitreal injection of anti-VEGF was very effective in diabetic macular edema. Improvement of diabetic macular edema was associated with improvement in best-corrected visual acuity.  

DOI

10.21608/scumj.2022.223251

Keywords

anti-VEGF, CME, BCVA, optical coherence tomography (OCT)

Authors

First Name

Ahmed

Last Name

Tawfek

MiddleName

Z.

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

ahmedzakaria@med.suez.edu.eg

City

-

Orcid

-

First Name

Mervat

Last Name

Elgharieb

MiddleName

E.

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Hussein

Last Name

Alnahass

MiddleName

S.

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Osama

Last Name

Alnahrawy

MiddleName

M.

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Amr

Last Name

Gab-Alla

MiddleName

A.

Affiliation

Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

amrophth@hotmail.com

City

-

Orcid

-

Volume

25

Article Issue

2

Related Issue

31648

Issue Date

2022-07-01

Receive Date

2022-03-07

Publish Date

2022-07-01

Page Start

7

Page End

11

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 25_Issue 2_Pages 7-11.pdf

PDF . 212.6kB

Link

https://scumj.journals.ekb.eg/article_223251.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=223251

Order

2

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023