A pot experiment was carried out under greenhouse conditions to trace the effect of water salinity and bacterial inoculation on growth parameters and nutrient uptake by lupin (Lupinus Albus L.). Experimental results showed that the growth parameters i.e. shoot and root dry weight and nutrient uptake by different plant parts were frequently affected by the effective factors. Dry matter yield of shoots was gradually increased with increasing water salinity levels. This phenomenon was more pronounced with 3 dS m^-1 rather than 6 dS m^-1 water salinity level. This holds true with all inoculation treatments. Similar trend was noticed with root dry matter yield but only in case of uninoculated treatment while the other inoculants reflected decline trend with increasing water salinity levels up to 6 dS m^-1. N uptake by shoots was positively affected by water salinity levels under bacterial inoculation except the dual treatments where N uptake tended to decrease with increasing water salinity levels. N uptake by roots was severely affected by increasing water salinity levels as compared to fresh water treatment. N uptake by shoots was enhanced by inoculation under different water salinity levels as compared to the uninoculated treatment. Nitrogen uptake by roots was dramatically affected by inoculation. It was only increased by inoculation when plants were irrigated with fresh water. Acquisition of K by shoot and roots of lupin plants was frequently affected by either water salinity or bacterial inoculation. Concerning the effect of bacterial inoculation, in general, the values of K-uptake by  shoots was increased due to inoculation treatments. Opposite direction was noticed with root-K where it decreased with inoculation treatments comparable to uninoculated one. Sodium uptake by shoot and root was positively affected by either increasing water salinity levels or bacterial inoculation. It is obvious that Na absorption was gradually increased with increasing water salinity levels up to 6 dS m^-1. This holds true under all inoculation treatments. Also, the results of both shoots and roots were nearly closed to each other. Generally, the highest values of Na content in shoots or roots were recorded with 6 dS m^-1 water salinity level.