Laboratory experiment was conducted in Plant Protection Research Institute Agriculture Research Station Sabahia Alexandria. This study aimed to investigate the efficiency of some natural-oil and mineral-oil against Pfannococcus cr‘tri (Risso) .Also to study the effect of the same compounds with mixed sisi-6-oil against the citrus mealy bug, plannococcus cftri (Risso). The results were recorded after 24, 48, 72 and 96 hours of treatment. The obtained data showed that the garlic-oil and neem-oil were the most toxic to the female of Piannococcus citri. The tested natural-oil had significant effect except the kz-oil on the P. citrr' 96hrs after treatment with the high dose (1.5ml.).The toxicity of tested materials and mixedsisi-S-oil were highly significant with more time and concentrations. However, garlic-oil with mixed sisi-6-oil was the most toxic after 96 hours of treatment against the citrus mealy bug at L650 level (0.449%), followed by onion +sisi-6-oil,neem+sisr-6-oi|,citrone||a+sisi-6-oi| and kz—oil+sisi-6-oil with L050 of 0.565,0.571,D.925 and 095%.