Twenty four prickly lettuce genotypes were studies for phenotypic and genotypic variability. broad sense heritability (his). phenotypic coefficient of variation (PCV). genotypic coefficient of variation (GCV%), genetic advance (GA%) of yield and yield components, selection index (SI), phenotypic and genotypic correlation and path coefficient. Significant variations were observed between genotypes for most studied traits during the two seasons (20032004 and 2004f2005).The highest genotypic and phonotypic variations were observed for oil yield, seed yield and number of branchesfplant, respectively. All the traits showed high heritability values with high genetic advance except for number of branchesfplant in both seasons. Selection index (St) was estimated for all genotypes of prickly lettuce. Genotypes number : 20, 8, 1 and 2 are considered to be promising for oil yield and oil content. Path coefficient analysis revealed the importance of seed yield per plant and oil content of all genotypes in both seasons. In general. results of genetic parameters (P.C.V, G.C.V. habits, GA%, and SI and path coefficient analysis) showed the importance of all or most studied traits especially seed yieldfplant, oil content % and oil yieldiplant as selection criteria in prickly cl: lettuce crop.