The aim of this study was aimed to assess the variations amongst a half diallel cross using six varieties for pollution characters, estimating combining ability and heterosis. This investigation was carried out at two locations i.e., the first, at Zarzora Farm, El-Behira Governorate (normal condition) and the second at Kafr El-Zaiyat area El-Gharbia Governorate, Egypt (pollution condition)  during the two seasons 2008/09 and 2009/10. Six diverse wheat varieties (Triticum aestivum, L.) and 15 F₁'s were planted in two experiments. The ratios of GCA/SCA were greater than unity under the two environments and the combined analysis for all traits, except total chlorophyll and 1000-grain weight under stress and the combined analysis, plant height under normal and the combined analysis, flag leaf angle, NO. of spikes per plant and grain yield per plant under the two environments and their combined. These results suggested predominant role of additive type of gene action for these traits and the potential for obtaining further improvements of these traits by using pedigree selection program. The best parental combinations were ; Ug2 X Sahel1, Ug2 x Gem.9 and Ug3 x Sahel 1 for most studied traits. The crosses;  Ug2 X Sahel1, Ug2 x Gem.9 and Sids 1 x Sahel 1 expressed parental heterosis for most traits which indicates that these crosses could be used in breeding program for pollution tolerance.