Four field experiments were conducted at Sakha Agriculture Research Station, Kafr El-Sheikh Governorate during 2011 and 2012 seasons. Early and late sowing experiemnts were carried out in the first season and repeated in the second season. These experiments were conducted to study the response of hybrid cotton 10229 x Giza 86 to agricultural systems, i.e., 43077 plants/fed. (65 cm ridge width and 30 cm hill spacing on one side), 36923 plants/fed. (65 cm ridge width and 35 cm hill spacing on one side), 48000 plants/fed. – (100 cm ridge width and 35 cm hill spacing on two sides) and 42000 plants/fed. (100 cm ridge width and 40 cm hill spacing on two sides) and nitrogen levels of 45, 60 and 75 kg/fed. Plants were thinned to two plants per hill after the formation of the second true leaf. Two of these experiments were carried out for the early sowing (15 April), but the other two experiments for the late sowing (15 May). The treatments carried out in the early planting also applied in the late sowing. The results can be summarized as follow: 1.  Increasing plant population density significantly increased final plant height, number of monopodia, number of sympodia per plant, number of main stem internodes/plant, nodal position of first sympodium, shedding percentage, number of open bolls and unopen bolls/plant, boll weight and seed cotton yield (kentar/fed.) in the two seasons. However, earliness percentage and percentage of plant losses/fed. significantly decreased by increasing plant density. 2.  There were significant differences among the three nitrogen levels, in all growth, earliness characters and yield and its components. Application of 75 kg N/fad. produced the highest values of plant height, number of monopodia and sympodia/plant, number of main stem internodes/plant, nodal position of the first sympodium, number of open and unopen bolls, boll weight and seed cotton yield (kentar/fed.), while the lowest nitrogen level (45 kg N/fed.) produced the lowest values of earliness %, shedding % and stand losses % at harvest. Seed index, lint percentage and fiber properties insignificantly affected by all treatments. The interaction between agricultural systems and nitrogen levels attained insignificant effect on all traits. 3.  The results showed that late sowing took the same direction as early planting and were higher values for the number of bolls, boll weight, yield and its components.                 In general, it can be stated that early sowing (15 April) of hybrid cotton 10229 x Giza 86 with 75 kg N/fed. and higher density 48000 plants/fed (100 cm ridge width and 35 cm hill spacing on two sides) induced higher seed cotton yield.