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196140

Wilms' tumor may be a rare presentation of ovarian neoplasms in girls

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Cell-based therapy against cancer

Abstract

Extrarenal Wilms' tumor is a rare malignant disorder. It represents 0.5-1% of Wilms' tumor. Management for ERWT is challenging regarding its pathological diagnosis, staging, treatment and prognosis. Here we report a 4 years old girl, presented with huge pelvi abdominal mass originating from the left ovary which was seen by radiologic assessment as a large lobulated heterogeneously enhancing mixed solid and cystic retroperitoneal mass away from both kidneys, occupying most of the abdomen with pelvic extension; it was displacing bowel loops and pancreas, measuring 13 x 15 x 16 cm without evidence of enlarged lymphadenopathy. The mass was diagnosed postoperatively as an extrarenal Wilms' tumor proved by immunohistochemical staining for Wilms' Tumor1 (WT1) with the negative reaction for other markers that exclude other diagnostic possibilities. The patient had an aggressive presentation and advanced disease. The diagnosis was difficult due to the lack of specific radiologic stigmata and aberrant origin. She was treated with aggressive chemotherapy to suit the advanced stage of her disease and unfavorable histology pattern.

DOI

10.21608/jcbr.2021.49736.1094

Keywords

Wilms, Ovary, Aggressive

Authors

First Name

Suzy

Last Name

abdelmabood

MiddleName

-

Affiliation

Pediatric Hematology and Oncology Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University, Egypt.

Email

suzyabdelmabood@yahoo.com

City

-

Orcid

-

First Name

Heba

Last Name

Sheta

MiddleName

-

Affiliation

Pathology Department, Faculty of Medicine, Mansoura University, Egypt.

Email

heba_sheta@yahoo.com

City

-

Orcid

0000-0002-4771-1120

First Name

Sherif

Last Name

Abdelmaksoud

MiddleName

-

Affiliation

Pediatric Surgery Department, Faculty of Medicine, Mansoura University. Egypt.

Email

sherifmohd@hotmail.com

City

-

Orcid

-

First Name

Basel

Last Name

Refky

MiddleName

-

Affiliation

Surgical Oncology Department, Faculty of Medicine, Mansoura University, Egypt.

Email

dr.basel@hotmail.com

City

-

Orcid

-

First Name

Niveen

Last Name

Abo Touk

MiddleName

-

Affiliation

Clinical Oncology and Nuclear medicine Department, Faculty of Medicine, Mansoura University, Egypt.

Email

nivabotouk@gmail.com

City

-

Orcid

-

First Name

Dina

Last Name

Harb

MiddleName

-

Affiliation

Radiology Department, Faculty of Medicine, Mansoura University, Egypt.

Email

drdinaharb84@yahoo.com

City

Mansoura

Orcid

-

First Name

Ahmad

Last Name

Darwish

MiddleName

-

Affiliation

Pediatric Hematology and Oncology Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University, Egypt.

Email

ahmad_darwish_77@yahoo.com

City

Mansoura

Orcid

-

Volume

5

Article Issue

3

Related Issue

27855

Issue Date

2021-09-01

Receive Date

2020-11-13

Publish Date

2021-09-01

Page Start

87

Page End

93

Print ISSN

2682-261X

Online ISSN

2682-2628

Article File

JCBR_Volume 5_Issue 3_Pages 87-93.pdf

PDF . 27.9MB

Link

https://jcbr.journals.ekb.eg/article_196140.html

Detail API

https://jcbr.journals.ekb.eg/service?article_code=196140

Order

9

Type

Case Report

Type Code

1,232

Publication Type

Journal

Publication Title

International Journal of Cancer and Biomedical Research

Publication Link

https://jcbr.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023