Background: Corona Virus overwhelmed many countries' healthcare systems, causing high levels of conflict amongst frontline nurses. Aim: To explore the conflict level and communication gap amongst the critical care nurses during the care of patients with COVID-19. Subjects and Method: Design:  A descriptive exploratory design was utilized. Setting:    The study implemented at the intensive care units (ICUs) affiliated to Abo Khalifa Emergency Hospital in Ismailia City, Egypt   Subjects: A convenient sample of 80 nurses working at the critical care units affiliated with a specialized isolation hospital in Ismailia City, Egypt, from July to September 2020. Tools:  tool one  a self-administered conflicts and communication gap questionnaire, which contained three parts (Nurses' Personal characteristics profile, Nursing Conflict Scale (NCS),  and Rahim Organizational Conflict Inventory-II form C, to assess staff nurses' preferred conflict resolution strategies. Results clarified that conflict was experienced by all critical care nurses, with 42.5% of the studied nurses have had moderate conflict, with the most common factors precipitating conflict being recurrent contact with infected patients and fear of infection for themselves and their loved ones by all the entire nurses (100%). Conflict types reported by the critical care nurses were intergroup, intrapersonal, competitive, intragroup, interpersonal, and disruptive by (3.59±1.43, 3.40±1.31, 3.21±1.24, 3.17 ±1.32, 2.93±1.23, and 2.47±1.41) respectively, with a statistically significant positive correlation between the level of conflict and collaboration, compromise, and avoiding conflict management styles (p-value.036,.002, and.000 respectively). Conclusion: Slightly less than half of nurses had moderate conflict levels, and collaborating was the most common used conflict resolution strategy, with the least one being avoidance. Recommendations: Training in conflict resolution strategies during outbreaks of terrorism as COVID- 19.