Background: Today's, the neonatal discharge planning care has been an indispensable component of neonatal intensive care. However, this comes with various challenges. So, pediatric nurses must be able to provide effective nursing care and to be awareof their roles, to achieve successful discharge of baby from Neonatal Intensive Care Unit.Aim: to assess pediatric nurses'perception and practices regarding neonatal discharge from Neonatal Intensive Care Units. Study Design:  a descriptive design was utilized in this study.  Setting:The study wascarried out in NeonatalIntensive Care Units, at general hospitals in Port-Said Governorate, Egypt.Subjects andMethod: Sixty pediatricnurseswere included in the present study. Data were collected using NICU discharge practices questionnaire, andNICU discharge perception scale. Results: Themain finding of thisstudy revealed that all pediatric nurses hadpoor neonatal discharge practices, while the majority of them had good perception regarding neonatal discharge.Conclusion: There waspositive statistical significant correlation between pediatric nurses' practices andtheir perception regarding neonatal discharge.Recommendation:Continuous trainingprogramwas recommended for pediatric nurses to enhance their perception and improve their skills toward neonatal discharge.