Background : The aim of this study is to assess the patients knowledge and evaluate the effect of an educational program on patient outcome as an indicator of health status.Subject and Methods: A quasi-experimental design was used to assess the patient knowledge regarding congestive heart failure and evaluate the effect of implementing an educational program on patient outcomes .The setting of the study was conducted in the cardiac care units in three selected governmental hospitals in Port Said city , El-Nasr Hospital, General Port Said Hospital and Al-Tadamon Health Insurance Hospital (The total sample size was 108 patients).Two tools was developed and used by the researcher for data collection. Tool: Congestive heart failure patients Questionnaire is divided into two parts. Part (1): This part included knowledge assessment regarding congestive heart failure and clinical data questionnaire as socio-demographic data and patient history and clinical data. Part (2): This part included educational program for patients with congestive heart failure. Results: The results revealed that there was a significant improvement in the patient's knowledge about definition, types, incidence, signs and symptom, patient belief about congestive heart failure, psych statues, in the first evaluation (after 1 month) and second evaluation (after 3 months).Conclusion: Educational program has a significant improvement on the patient's knowledge regarding congestive heart failure.