A survey of weeds of different field crops, orchards and marginal lands were conducted in Bani Al-Hareth area in Sana'a governorate at the High Land region of Yemen, during the period from December 2011 to September 2012. This is to identify and classify the growing weed species in the study area and their spectrum which includes botanical composition, availability, density, coverage and fresh weight. A checklist of weed species found in the area is given. The checklist includes the scientific and vernacularnames, life cycle, life forms and availability. Forty-eight weed species belonging to 19 families are reported. Maximum numbers of weed species were belonged to the family Asteraceae followed by Solanaceae, Poaceae and Brassicaceae. Among the recorded species, weed species such as Flaveria trinervia, Tagetes minuta, Chenopodium murale, Salsola kali, Cynodon dactylon, Fagonia indica and Aerva javanica were found to be the most weeds were recorded in all studied lands. Weed plant species in marginal lands had the highest values as compared with those of field crops and orchards ones for most the studied characteristics such as plant density, coverage and fresh weight.