ABSTRACT
Primary open angle glaucoma is a multifactorial disorder characterised by the death of retinal ganglion cells, which results in a characteristic optic neuropathy and concomitant visual field reduction.

Aim of the work: is to determine the association between central corneal thickness, intraocular pressure, peri-papillary retinal nerve fiber layer thickness, and ganglion cell layer thickness in patients with primary open angle glaucoma.

Patient and methods: A cross-sectional observational study included 60 eyes of 36 patients with primary open angle glaucoma conducted at the Ophthalmology Department, Al Azhar University Hospitals between April 2020 and April 2021.

Results: We found a significant negative correlation between corrected IOP Versus total, superior and inferior GCL+ in the studied POAG patients. There was also significant negative correlation between corrected IOP Vs. total, superior and inferior RNFL in the studied POAG patients. There is no significant correlation between CCT vs. IOP, macular GCL, Total RNFL or superior RNFL thickness while there was a positive correlation detected between CCT and inferior RNFL in the studied POAG cases.

Conclusion: In the studied POAG cases, we found positive associations between CCT and inferior RNFL, but no significant association between CCT and IOP, macular GCL, Total RNFL, or superior RNFL thickness.