Background: multiple sclerosis is an immune-mediated inflammatory disease that attacks
myelinated axons in the central nervous system, destroying the myelin and the axon in the variable
degrees. It is lifelong condition that can sometimes cause disability, although it can occasionally be

The nurses have a vital role to play at all stages of MS but arguably involvement when patient

is newly diagnosed in the most crucial stages. Aim of study: this study aimed to assess nurses'
performance regarding the care of patients with multiple sclerosis relapse. Study design: A
descriptive explanatory design. Setting: day care unit at the neurological department affiliated to
Ain Shams University Hospital. Study subject: A convenient sample of nurses (n =30) working in
the selected setting. Tools: I Nurses interviewing questionnaire, II Nurses practice observational
checklist and III Nurses attitude likert scale. Results revealed that 63.3%of the studied nurses had
unsatisfactory level of knowledge, 70%of them had unsatisfactory level of practice and 53.3 of
them have negative attitude regarding the care of patients with multiple sclerosis relapse.
Conclusion: less than two thirds of the studied nurses had unsatisfactory level of knowledge, less
than three quarters of them had unsatisfactory level of practice and around half of them had negative
attitude regarding the care of patients with multiple sclerosis relapse. Recommendation: In-service
training program must developed based on nurses performance regarding the care of patients with
multiple sclerosis relapse