Background: Infection prevention and control are challenging in most health care settings,
and rising rates of infectious diseases are a major concern for patients and health care professionals.
Aim : this study aimed to assess nurses' performance regarding isolation precaution measures
application in emergency department. Subjects and method: A descriptive design was used. The
study was conducted in emergency departments at El-Fayoum university hospitals. A convenient
sample of all available nurses (60 nurses) in previous mentioned setting to achieve the aim of the
study. Two data collection tools was utilized in this study: Self-administered questionnaire, and
observation checklist. Results: 66.7% of the studied nurses had unsatisfactory total level of
knowledge. 75% of the studied nurses had unsatisfactory total level of performance. Conclusion:
The current study concluded that more than two third studied of nurses had unsatisfactory level of
knowledge. While, three quarters of them had unsatisfactory level of performance. Correlation:
There is a highly statistically significant positive correlation between nurses' total knowledge and
their total performance. Recommendations: The current study recommended that providing
training programs for nurses regarding application of isolation precaution measures in emergency
department and further studies should be conducted in different settings.