Background: Healthcare workers (HCWs) especially nurses are the backbone of the healthcare
system and a skilled and healthy workforce is vital during a health crisis, such as the present coronavirus
disease 2019 (COVID-19) pandemic. So, studying nurses' knowledge of COVID-19 and compliance
with protective measures is necessary. Aim of the study: this study aimed to assess maternity staff
nurses' knowledge and compliance for protective measures against coronavirus. Study design: A
descriptive study design was used. Sample: Purposive sample of 76 maternity staff nurses was recruited
from Obstetrics and Gynecology Departments, and Maternal child health centers based on certain
inclusion criteria. Setting: The study was conducted at the Obstetrics and Gynecology Department of
three governmental hospitals in El-Fayoum governorate, (Fayoum General Hospital, university hospital,
and Itsa Central Hospital) and three from total five Maternal child health centers in El-Fayoum city ( El
sheikh Hassan, El hadka, El sad el aaly). Two tools of data collection were used. I): Arabic structured
interviewing questionnaire sheet and II) Maternity staff nurses' Compliance scale for protective measures
against coronavirus. Result of the study indicated that 73.7% of maternity nurses had satisfactory
knowledge of COVID-19 infection and only 35.5% of maternity nurses had compliance with protective
measures against coronavirus. Conclusion: nearly three-quarters of maternity nurses had satisfactory
knowledge of COVID-19 infection, and nearly two-thirds of maternity nurses hadn't compliance with
protective measures against coronavirus. Recommendation: Design and implement a motivational
program for maternity staff nurses to promote their compliance with protective measures during the
covid-19 pandemic. Also, recommend further research to study barriers to compliance with protective
measures among maternity staff nurses during the covid-19 pandemic.