Background: The success of heath organizations depends on not only capacity to survive but even
more so on its ability to continuously adapt and change. Agile nurse leaders require not to be afraid
of change, but to renew their selves regularly to provide competitive advantage. Aim: The study
aimed to determine the effect of educational program about head nurses' agile leadership on staff
nurses' workplace spirituality and job reputation. Design: A quasi-experimental research design
Setting: The study was conducted in all units at Benha University Hospital. Subjects: Two groups
were included in this study; convenient sample (head nurses group; n=80) and purposive sample
(staff nurses group; n=310). Tools: Four tools were used in this study; (1): Agile Leadership
Knowledge Test, (2): Agile Leadership Practice Self-administered Questionnaire, (3): Workplace
Spirituality Questionnaire and (4): Job Reputation Questionnaire. Results: The study findings
revealed that there were statistical significant improvement in head nurses' agile leadership
knowledge and practice, and staff nurses' perception level regarding workplace spirituality and job
reputation after implementation of educational program. Conclusion: There were statistically
significant positive correlation among head nurses' agile leadership knowledge and practice and
staff nurses' workplace spirituality and job reputation scores. Recommendation: Supporting
organizational culture that contribute to the growth of the concept and strategies of agile leadership
and its effect on the workplace spirituality and job reputation.