Background: Hepatitis C virus infection is a community and pediatric problems,
needs for supporting their mothers to decrease their strains and powering their children
quality of life. Aim: To examine effect of family empowerment nursing intervention on
caregivers' strains and health-related quality of life of children with hepatitis C. Design: A
quasi-experimental research design. Setting: The study was carried out at outpatient clinics
in National Liver Institute at Shebin El-Kom, Menoufia University, Egypt. Sample:
Purposive sample composed of 160 caregivers and their children with hepatitis C were
recruited. Tools of the study: 1. Structured interviewing questionnaire. 2. Modified Index of
Caregivers' Strain 3. Pediatric Quality of Life Inventory Version 4. Results: The main
findings of current study showed that at pre family empowerment intervention, most (90%)
of family caregivers had suffering from high level of strains while only 10% had low level of
strains compared to post family empowerment intervention, there was statistically significant
decreased in high level of caregivers' strain. Additionally, there was statistical significance
improvement in the quality of life of children having hepatitis C; at post family
empowerment intervention compared to pre intervention. Conclusion: Family empowerment
intervention was effective in reducing family caregivers' feeling of strain and enhances
health related quality of life in children with hepatitis C. Recommendations: The need for
establishing health education units in every outpatient clinics to provide therapeutic
education to children and their family caregivers