Upper gastrointestinal endoscopy plays a major role in diagnosis and management of upper
gastrointestinal disorders . Endoscopy nurses play a critical role in ensuring that endoscopy is both
safe and of high-quality. Aim: evaluate the effect of self-learning module on nurses' knowledge and
safety practices concerning care of patients undergoing upper gastrointestinal endoscopy. Design: A
quasi experimental research design (pre and post-test) was utilized. Setting: in the endoscopy unit
at Homeyat Elabassia Hospital. Sample: A convenient sample of all available nurses (60 nurse)
working at the previously mentioned setting. Tools of the study: Two tools were used, the first tool
was structured self-administrated questionnaire: it was consisted of two parts; demographic
characteristics of nurses and nurses' Knowledge. The second tool was nurses' safety practices
observational checklist. Results: Mean age of studied nurses was 27.9 ± 4.71. 23.3% of the studied
nurses had satisfactory level of knowledge pre implementation of self-learning module which
increased to 76.7% post implementation with a highly statistically significant differences between
pre and post implementation at p=0.000. A highly statistically significant difference of total nurses'
safety practices between pre and post self-learning module implementation among the studied
nurses. There was a direct statistically significant correlation between total knowledge and total
safety practices of studied nurses. Conclusion: There was a positive effect of self-learning module
on nurses' knowledge and safety practices and there were highly statistically significant differences
in total nurses mean score of knowledge and practices between pre and post implementation of self-
learning module. Recommendations: Periodic in-service training to maintain and update level of
knowledge and safety practices of nurses working at endoscopy unit.