Background: Acute Coronary Syndrome outcomes continue to be one of the most
powerful measures of quality care in all health care settings for all caregivers. Nurse-sensitive
outcome measurement is one of the most promising strategies that can enhance patient care and
satisfaction of patients, families, and caregivers. Aim: the aim of this study was to identify factors
affecting patients' outcomes after acute coronary syndrome. Design: A descriptive exploratory
design. Setting: the study was conducted in the Coronary Care Units (CCU) at Ain Shames
University hospital. Study subjects: A Purposive sample of 100 patients was included in this
study. Tools of data collection: I-Interview questionnaire sheet. II-Patients' outcomes assessment
tool .Results: The present study reveals that about half of the patients suffering from acute
myocardial infarction with st-elevtion. The present study reveals that less than half of the patients
suffering from diabetes mellitus and hypertension. The present study revealed that all patients
under study weren't compromised for peripheral tissue perfusion and medication response at
physical health outcomes. These study finding that there are highly statistically significant
positive correlations between physiological healths outcomes, psychological and social health
total outcomes. Conclusion: Furthermore, there were many factors affecting patients' outcomes
such as: work status, age of patients, educational level, monthly income, present and past health
history. Recommendations: Health education regarding eliminating the risk factors of ACS
.Establishment of centers for screening the clients at risk for ACS. More research into biological
and psychosocial aspects of health outcomes is needed in order to increase the understanding of
ACS and to develop more effective interventions.