Background: Regardless of the early stages of their condition, hypertensive people exhibit diastolic and subclinical systolic dysfunction. Objective: This study aimed to evaluate the accuracy of M-Mode Apical Systolic Excursion (MMASE) to identify subclinical systolic dysfunction in hypertensive sufferers in comparison to left ventricular global longitudinal systolic strain (LV GLS) determined by 2D-Speckle tracking echocardiography (2D-STE). Patients and methods: In this case-control survey; demographics, clinical information, conventional echocardiography, tissue doppler imaging (TDI), and 2D-STE were examined in 56 hypertensive individuals with normal ejection fraction (EF), vs 28 healthy people. In order to determine MMASE. M-Mode vector was applied through the left ventricle's apex in an apical four-chamber view, and the endocardial excursion between end diastole and end systole was measured. Results: MMASE and LV GLS revealed a strong positive correlation (P< 0.001). After implementing the ROC curve in comparison to the gold standard LV GLS, we said that MMASE has a cut off value for identification of subclinical systolic dysfunction below 0.6 cm. Conclusion: In patients with hypertension, MMASE is a helpful M-mode assessment in the early diagnosis of subclinical LV systolic malfunction validated by a decrease in global LV longitudinal systolic strain.