The main objective of this paper is to use six sigma methodology for cost reduction and raising efficiency of human resource's performance. the researchers relied on theoretical rooting through the extrapolative approach of Arabic and foreign books, references and studies. Also the researchers relied on Collect data through personal interviews, records and reports, Accordingly the analytical approach to describe the problem and analyze the results of the research. The most important results indicate that six sigma implementation can reduce costs especially costs of electric power, and it's able to development of personnel performance through identifying the causes related the deviation and variation, then solving these causes by scientific method depends on logic and neutrality. The researchers recommend that a skills of human resources in airports sector at Egyptian airports should be considered, as well as attention to the strategic management of the costs, finally the study recommends supporting future studies related to six sigma methodology and it's impact on cost reduction and human resources development.