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204364

DIAGNOSIS OF ALZHEIMER'S DISEASE BY THREE-DIMENSIONAL CONVOLUTIONAL NEURAL NETWORK USING UNSUPERVISED FEATURE LEARNING METHOD

Article

Last updated: 22 Jan 2023

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Abstract

The rise of Deep Learning in the past two decades has prompted research into solutions to help improve Alzheimer's diagnosis based on neuroimaging data. As such, a wide variety of different techniques have been used, but a clear turn towards the use of Convolutional Neural Networks (CNN) has been observed in the last decade. To effectively predicate Alzheimer's Disease (AD), this paper proposed a two stage method. The first stage involves learning the best representation of the training data using an improved sparse autoencoder (SAE), an unsupervised neural network. The second stage involves using a 3D-Convolutional Neural Network (3D-CNN) to differentiate between the health status and diseased status based on the learned records and MRI scan of the brain. The SAE was optimized so as to train an efficient model. We report on experiments using the ADNI data set involving 897 historical scans. We demonstrate that using 3D convolutional neural networks with sparse auto encoder outperform several other classifiers stated in the literature.

DOI

10.21608/ijicis.2021.80596.1103

Keywords

Alzheimer's disease (AD), Sparse autoencoder (SAE), 3D-Convolutional Neural Network (3D-CNN), Feature Learning

Authors

First Name

Sarah

Last Name

A. Soliman

MiddleName

-

Affiliation

Higher Technological Institure,Cairo,Egypt

Email

sara_cs2003@hotmail.com

City

Cairo

Orcid

-

First Name

El-Sayed

Last Name

A. El-Dahshan

MiddleName

-

Affiliation

Egyptian E-learning University, Cairo,Egypt

Email

e_eldahshan@yahoo.com

City

Cairo

Orcid

-

First Name

Abdel-Badeeh

Last Name

M. Salem

MiddleName

M.

Affiliation

Computer Sciece Department, Faculty of Computer and Information Sciences, Ain Shams University

Email

absalem@cis.asu.edu.eg

City

Cairo

Orcid

0000-0001-5013-4339

Volume

22

Article Issue

1

Related Issue

31259

Issue Date

2022-02-01

Receive Date

2021-06-13

Publish Date

2022-02-01

Page Start

1

Page End

15

Print ISSN

1687-109X

Online ISSN

2535-1710

Link

https://ijicis.journals.ekb.eg/article_204364.html

Detail API

https://ijicis.journals.ekb.eg/service?article_code=204364

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1

Type

Original Article

Type Code

494

Publication Type

Journal

Publication Title

International Journal of Intelligent Computing and Information Sciences

Publication Link

https://ijicis.journals.ekb.eg/

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Article

Created At

22 Jan 2023