This study attempted to investigate the effect of using Wordfast Anywhere computer-assisted translation (CAT) tool on developing the EFL translation skills of English majors whose inefficiency in such skills constituted the rationale of the present study. Participants (N = 48) were chosen at random from second year students enrolled in the English Department at the Faculty of Education, University of Sadat City, during the first semester of the 2019-2020 academic year. They were divided into two groups: an experimental group (n = 24) and a control one (n = 24). An EFL translation skills test was developed and administered before and after experimentation that lasted for seven weeks. The experimental group students were taught using Wordfast Anywhere while the control group students received regular instruction. Results revealed that students of the experimental group achieved significant improvement in EFL translation skills. Thus, using Wordfast Anywhere proved to have a positive effect on developing English majors' EFL translation skills.