Background: Preeclampsia is a pregnancy specific syndrome that can affect every system in the body. Preeclampsia can be categorized into severe" and “non-severe." According to the blood pressure measurement and presence of proteinuria. Urinary tract infections are the most common medical complication of pregnancy with an estimated incidence of approximately 20%. UTIs in pregnancy have been associated with increased risks of chorioamnionitis and endometritis. About the fetus, it has been shown that UTI is associated with fetal growth restriction, stillbirth, preterm labor, and delivery, increased perinatal mortality, mental retardation, and developmental delay.
Methods: This was a prospective cross-sectional study conducted on 50 patients whom were diagnosed with preeclampsia and were admitted to El Shatby university hospital. Based on Urinary tract infection, two groups were enrolled; Group A (25 cases) included preeclamptic patients without urinary tract infection and Group B (25 cases) included preeclamptic patients with urinary tract infection. Results: Urine culture and Bacterial identification were performed in preeclamptic patients with UTI (group B=25). E. coli was responsible for 68 % of the cases, Klebsiella was found in 12 % of the cases, Pseudomonas was found in 12 % of the cases, Methicillin-resistant Staphylococcus aureus (MRSA) was found in 4 % of the cases and Methicillin-resistant coagulase-negative staphylococci (MR-CONS) was found in 4 % of the cases. Protein creatinine ratio has been correlated statistically with the total number of signs of severity in each group and the total sample. There was no significant correlation between them in group A (r = 0.064, P = 0.763) while there was positive significant correlation between them in group B (r = 0.501, P = 0.011) and the total sample (r = 0.734, P <0.001) Conclusion: Protein creatinine ratio positively correlates with the severity of preeclampsia. Urinary tract infection (UTI) during gestation is associated with increased severity of preeclampsia. Escherichia coli was found to be the most prevalent organism isolated in preeclamptic patients with UTI.