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257487

Intrauterine contraceptive device versus barrier methods for breast cancer women undergoing postoperative chemotherapy: A randomized controlled trial

Article

Last updated: 03 Jan 2025

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Abstract

Objective: to compare the effectiveness of intrauterine device and the
barrier methods of contraception in the form of male condom during the
postoperative chemotherapy period in patients with breast cancer at the
reproductive age.
Study design: A randomized controlled clinical study enrolled married patients, aged ≤ 44 yearswith breast cancer scheduled for chemotherapy. Group (A) (n=51) randomly used intrauterine device and group < br />(B) (n=51) used male condom for contraception.
Results: Although patients' menstrual patterns showed no significant differences at the entry to the study, patients in group (A) showed heavier cycles when evaluated after 3m and again after 6m form the onset of
the chemotherapy. The duration of bleeding (mean ±SD) was 7.7±1.7 and
5.6±1.3 in group A and B respectively after 3m and significant changes in
the cycle length and the duration of bleeding after 6m had occurred. Likewise, the incidence of genital tract infection was higher in the group using
intrauterine device while receiving chemotherapy.
Conclusion: While intrauterinecontraceptive device was always considered as the method of choice for most of the malignant patients, this study
showed that it is more practical to use the barrier methods at least during
the chemotherapy cycles in order to minimize the associated hazards of
chemotherapy induced bone marrow depression on the safety of intrauterine device.

DOI

10.21608/egyfs.2015.257487

Keywords

Key Words: Breast cancer, Reproductive age, Intrauterine contraceptive device, barrier methods

Authors

First Name

Hanan

Last Name

Nabil

MiddleName

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Affiliation

3Department of Obstetrics and Gynecology, Faculty of Medicine, Mansura University, Egypt.

Email

hanannobil00@yahoo.com

City

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Orcid

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Volume

19

Article Issue

1

Related Issue

36463

Issue Date

2015-01-01

Receive Date

2022-09-01

Publish Date

2015-01-01

Page Start

11

Page End

16

Print ISSN

1110-6352

Online ISSN

2536-9768

Article File

EGYFS_Volume 19_Issue 1_Pages 11-16.pdf

PDF . 2.0MB

Link

https://egyfs.journals.ekb.eg/article_257487.html

Detail API

https://egyfs.journals.ekb.eg/service?article_code=257487

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2

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

Intrauterine contraceptive device versus barrier methods for breast cancer women undergoing postoperative chemotherapy: A randomized controlled trial

Details

Type

Article

Created At

22 Jan 2023