Background: Hemodynamic instability is defined as any instability in blood pressure which can lead to inadequate arterial blood flow to organs.Wernovsky-inotropic score (WIS), a measure of post-operative cardiovascular support, has been associated with morbidity and mortality after infant cardiac surgery in prior center studies.
Objectives: This study aimed to determine the association of Wernovsky-inotropic score (WIS) with clinical outcome of critically ill children with hemodynamic instability in PICU and to use it as a predictor of the outcome of the critically ill patients.
Patients & Methods:This study was prospective analytical study which conducted at pediatric intensive care unit (PICU) at Pediatric Department, Zagazig University Hospital on 102 patients during the period of 10 months from april 2018 to January 2019.
Results: On studying relationship between WIS score over time and patient outcome, WIS didn't statistically significantly differ between dead or discharge patients at baseline, 6 and 12 hours. While there is significant difference between both groups at 24 and 48 hours.
Conclusions: Wernovssky-inotrpic score (WIS) is an easily calculated clinical score. It is useful as an independent predictor of clinical outcomes of critically ill pediatric patients with hemodynamic instablility in PICU. WIS is a reliable marker of cardiovascular support that may be used as a surrogate outcome for research studies and provide additive value to existing pediatric acuity scores in this population.
Keywords: Wernovesky-Inotropic Score.