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61486

Evaluation of Anti-Rheumatoid Arthritis Activity of White, Black Mulberry and Turmeric in Complete Freund's Adjuvant Induced Rheumatoid Arthritis Rats

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Last updated: 01 Jan 2025

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Abstract

Abstract
Background: Rheumatoid arthritis (RA) is an autoimmune disorder which affects 0.5-1% of the adult population. RA affects any age group, including children, but is mostly diagnosed between the ages of 40-55 years.
Aim of Study: The aim of this investigation is to evaluate of anti-rheumatoid arthritis activity of white mulberry, black mulberry and turmeric in complete freund's adjuvant induced rheumatoid arthritis rats.
Materials and Methods: A total of 40 male albino rats weighing (140±10g) were used in this study. Rats were divided into 8 group, first group fed on basal diet as a control negative group, the second group were injected by 0. 1ml of complete fruend's adjuvant and used as a positive control group ,while the other groups were fed on basal diets blended with 5-10% of the white mulberry, black mulberry, turmeric as powder for 28 days.
Results: The results showed that turmeric, black mulberry and white mulberry record the better results in Erythrocyte Sedimentation Rate (ESR), and C reactive protein (CRP) at entry, Rheumatoid factor (RF), Anti cyclic citrullinated peptide (Anti-CCP) because of its anti-cancer, anti-inflam-matory, anti-diabetic, and anti-rheumatic properties associated with good tolerability and safety.
Conclusion: The study recommends the tested medicinal plants are useful for healing as well as for curing of human diseases because of the presence of phytochemical constituents.

DOI

10.21608/mjcu.2018.61486

Keywords

Rheumatoid arthritis – Complete Freund's Adju-vant – Anti-inflammatory – The medicinal plants and Mulberry

Authors

First Name

SAHAR O. EL-SHAFAI, Ph.D.;

Last Name

EMAD M.A. EL-KHOLIE, Ph.D.

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First Name

FATMA M.H.

Last Name

ABO EL-NOR, M.Sc.

MiddleName

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Affiliation

The Department of Nutrition & Food Science, Faculty of Home Economics, Menufia University

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Volume

86

Article Issue

December

Related Issue

9163

Issue Date

2018-12-01

Receive Date

2017-11-25

Publish Date

2018-12-01

Page Start

3,715

Page End

3,722

Print ISSN

0045-3803

Online ISSN

2536-9806

Link

https://mjcu.journals.ekb.eg/article_61486.html

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https://mjcu.journals.ekb.eg/service?article_code=61486

Order

42

Type

Original Article

Type Code

263

Publication Type

Journal

Publication Title

The Medical Journal of Cairo University

Publication Link

https://mjcu.journals.ekb.eg/

MainTitle

Evaluation of Anti-Rheumatoid Arthritis Activity of White, Black Mulberry and Turmeric in Complete Freund's Adjuvant Induced Rheumatoid Arthritis Rats

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Article

Created At

22 Jan 2023