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5909

THE PROTECTIVE ROLE OF ASCORBIC ACID (VITAMIN C) ON NEUROTOXICITY OF OELTAMETHRIN ON THE SCIATIC' NERVE OF ALBINO RAT

Article

Last updated: 22 Jan 2023

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Abstract

Synthetic pyrethroid insecticides had been widely used (in agriculture, home pest control and disease vector control) for their high activity as an insecticide and low mammalian toxicity. This low mammalian toxicity was due, in part, to their rapid metabolism in these animals (Dick et al., 1984). Pyrethroids had been subdivided into two classes based on their structural characteristics and pharmacological effects. Type I pyrethroids such as allethrin and permethrin do not contain c-cyano group, which is present in type II pyrethroids such as deltamethrin, cypermethrin and fenvalerate (Moya-Quiles et aI., 1996). The lipophilia of pyrethroids favored their absorption through the skin, gastrointestinal and respiratory tracts to be more distributed into lipid-rich internal tissues, including body fat and elements of the central and peripheral nervous system (Soderlund et aI., 2002). 

DOI

10.21608/ejana.2004.5909

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Authors

First Name

Mohamed

Last Name

Mostafa

MiddleName

-

Affiliation

Anatomy Department, Faculty of Medicine, Cairo University

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Orcid

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Volume

27

Article Issue

2

Related Issue

1058

Issue Date

2004-07-01

Receive Date

2018-04-05

Publish Date

2004-07-01

Page Start

205

Page End

225

Print ISSN

1110-2144

Online ISSN

2090-259X

Link

https://ejana.journals.ekb.eg/article_5909.html

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https://ejana.journals.ekb.eg/service?article_code=5909

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9

Type

Original Article

Type Code

231

Publication Type

Journal

Publication Title

The Egyptian Journal of Anatomy

Publication Link

https://ejana.journals.ekb.eg/

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Article

Created At

22 Jan 2023