BROADLEAF weeds cause severe competition with wheat crop in Egypt and its highly reduce yield. Two field experiments during two winter seasons were conducted in the Experimental Research Station of the Faculty of Agriculture, Cairo University, Giza Governorate, Egypt during winter seasons of 2014/2015 and 2015/2016. The aim of this work was to control broadleaf weeds in wheat and evaluate of 17 broadleaf weed herbicides in wheat (Triticum aestivum L.) CV. Gemeza- 11.Weed control treatments were hand pulling and applying 17 experimental post-emergence herbicides, were applied bromoxynil-octaneoate 24%, DICAMBA 48%, Tribenuron-Methyl 16 % + Carfentrazone-Ethyl 12%, MCPA-sodium 20%+Bromixanil 20%, Florasulam 0.25%+ Mesosulfuron-Methyl 0.75%, MCPA-sodium 36%+ Florasulam 1% , Florasulam 05%+ Clodinafop-propagyl 6.5%, Tribenuron-Methyl 2.7%+ Fluroxypyr 13.7%, Tribenuron-Methyl 5%+ Clodinafop-propagyl 10%, bromoxynil-octanoate 25%, Triasulfuron 4.1% + Dicamba 65.9 %, Tribenuron-Methyl 8%+ Fenoxaprop-p-Ethyl45%+ Thifensulfuron-Methyl 12%, Bromoxynil octaneoate, Florasulam 1.42%+ Pyroxsulam 7.08%,Florasulam 1.42%+ Pyroxsulam 7.08%+ Ecosurf, Tribenuron-Methyl and Fluroxypyr 10% + Florasulam .025% + Clopyralid 8%. Application of herbicides was after 25 days from sowing date in both seasons, and hand pulling twice after 25 and 45 days. Presented data showed that all weed control treatments (herbicides and hand weeding twice) reduced broadleaved weed density and weight. These treatments, increased wheat yield and yield components significantly compared to weedy check, except Florasulam 1.42%+ Pyroxsulam 7.08%, which recorded reduction in wheat yield. Triasulfuron 4.1% + Dicamba 65.9 %, gave the highest number of grains/ spikelet and spike per plant and straw yield t/ ha , and the best treatment in grain yield was Tribenuron-Methyl 2.7%+ Fluroxypyr 13.7% herbicide compared with weedy check.